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Efeitos do extrato de bagaço de uvas na esteatose hepática, uma avaliação in vitro
(2020-09-19)
A doença hepática gordurosa não-alcoólica (DHGNA) é uma das doenças hepáticas mais
comuns no mundo. A esteatose hepática, basicamente, pode ser definida como o acúmulo
de lipídios no fígado. Os compostos fenólicos dos ...
Researching new drug combinations with senolytic activity using senescent human lung fibroblasts MRC-5 cell line
(Pharmaceuticals, 2024-01-04)
Therapeutically targeting senescent cells seems to be an interesting perspective in treating
chronic lung diseases, which are often associated with human aging. The combination of the drug
dasatinib and the polyphenol ...
Bioaccessibility evaluation of soymilk isoflavones with biotransformation processing
(Revista Foods, 2023-09-12)
Soy isoflavones are considered important sources of bioactive compounds, but they are
poorly absorbable, due to their large hydrophilic structures. Some biotransformation strategies have
been used to convert the glycosidic ...
Effects of systemic inflammation due to hepatic ischemia-reperfusion injury upon lean or obese visceral adipose tissue
(Acta Cirúrgica Brasileira, 2022-03-14)
Purpose: To evaluate how the induction of liver damage by ischemia and reperfusion affects the adipose tissue of lean and obese mice. Methods: Lean and diet-induced obese mice were subjected to liver ischemia (30 min) ...
The impact of polyphenols-based diet on the inflammatory profile in COVID-19 elderly and obese patients
(Frontiers in Physiology, 2021-01-12)
The World Health Organization declared the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)-associated disease (coronavirus disease 2019 – COVID-19) as a pandemic in March 2020. COVID-19 is characterized by ...