Produção acadêmica e científica: Recent submissions
Itens para a visualização no momento 1341-1360 de 4081
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Antiobesity effects of yerba maté extract (Ilex paraguariensis) in high-fat diet–induced obese mice
(Wiley, 2009)Because the potential of yerba maté (Ilex paraguariensis) has been suggested in the management of obesity, the aim of the present study was to evaluate the effects of yerba maté extract on weight loss, obesity-related ... -
Modulatory effect of polyphenolic compounds from the mangrove tree Rhizophora mangle L. on non-alcoholic fatty liver disease and insulin resistance in high-fat diet obese mice
(MDPI AG, 2018)No scientific report proves the action of the phytochemicals from the mangrove tree Rhizophora mangle in the treatment of diabetes. The aim of this work is to evaluate the effects of the acetonic extract of R. mangle barks ... -
Bioaccessibility evaluation of soymilk isoflavones with biotransformation processing
(MDPI AG, 2023)Soy isoflavones are considered important sources of bioactive compounds, but they are poorly absorbable, due to their large hydrophilic structures. Some biotransformation strategies have been used to convert the glycosidic ... -
Evaluation of Budesonide–hydroxypropyl-β-cyclodextrin inclusion complex in thermoreversible gels for ulcerative colitis
(Springer Science and Business Media LLC, 2020)Background New formulations for topical treatment of ulcerative colitis with budesonide inclusion complex (BUDHP-β-CD) and poloxamers (PL) were developed for future clinical use. Aims This study evaluated the efcacy of ... -
The impact of Polyphenols-based diet on the inflammatory profile in COVID-19 elderly and obese patients
(Frontiers Media SA, 2021)The World Health Organization declared the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2)-associated disease (coronavirus disease 2019 – COVID-19) as a pandemic in March 2020. COVID-19 is characterized by ... -
The postprandial inflammatory response is attenuated by a dietary structured lipid containing behenic acid
(Elsevier BV, 2019)A high-fat meal can induce a postprandial inflammatory response, characterized mainly by increased serum levels of interleukin (IL)-6 and endotoxemia. We developed a structured lipid rich in behenic acid via enzymatic ... -
Effects of polyphenols on thermogenesis and mitochondrial biogenesis
(MDPI AG, 2018)Obesity is a health problem worldwide, and energy imbalance has been pointed out as one of the main factors responsible for its development. As mitochondria are a key element in energy homeostasis, the development of obesity ... -
Effects of grape pomace extracts in hepatic steatosis, uma avaliação in vitro
(Editora Científica Digital, 2020)A doença hepática gordurosa não-alcoólica (DHGNA) é uma das doenças hepáticas mais comuns no mundo. A esteatose hepática, basicamente, pode ser definida como o acúmulo de lipídios no fígado. Os compostos fenólicos dos ... -
The effect of guarana (Paullinia cupana) on metabolic and inflammatory parameters in adult male mice programmed by maternal obesity
(Springer Science and Business Media LLC, 2018)Purpose: Maternal obesity can program the offspring, increasing the risk of overweight and obesity in adult life. Guarana (Paullinia cupana) is a Brazilian plant that has weight-reducing effects. Thus, this study aimed to ... -
Addition of polyphenols to drugs: The potential of controlling “inflammaging” and fibrosis in human senescent lung fibroblasts in vitro
(MDPI AG, 2024)The combination of a polyphenol, quercetin, with dasatinib initiated clinical trials to evaluate the safety and efficacy of senolytics in idiopathic pulmonary fibrosis, a lung disease associated with the presence of senescent ... -
Impact of enzymatic soymilk isoflavones biotransformation for improved bioaccessibility and antioxidant capacity
(MDPI AG, 2023)Soy isoflavones are considered important sources of bioactive compounds, but they are poorly absorbable, due to their large hydrophilic structures. Some biotransformation strategies have been used to convert the glycosidic ... -
Could new palm-free structured lipids mitigate postprandial hyperlipidemia and inflammation induced by high-fat meals in swiss mice?
(Informa UK Limited, 2025)A high-fat meal can cause postprandial hyperlipemia, initiating an acute inflammatory response. New structured lipids (SLs) free from trans and palm fatty acids are emerging as food structurants. Objective: We evaluated ... -
Researching new drug combinations with senolytic activity using senescent human lung fibroblasts MRC-5 cell line
(MDPI AG, 2024)Therapeutically targeting senescent cells seems to be an interesting perspective in treating chronic lung diseases, which are often associated with human aging. The combination of the drug dasatinib and the polyphenol ... -
Hepcidin and inflammation associated with iron deficiency in childhood obesity - A systematic review
(Elsevier BV, 2024)Objectives This paper aims to review data on the association of obesity and iron deficiency in children and adolescents, exposing the possible involvement of hepcidin and interleukin-6 (IL-6), obesity's inflammation ... -
Structured nanoemulsion lipid as alternative to obesity control: An in vivo study
(SciVision Publishers LLC, 2024)Due to the global obesity epidemic, creating low-calorie foods for the industry is critical. Behenic acid, by partially inhibiting pancreatic lipase and decreasing fat absorption, is a promising option when included in ... -
Nitric oxide interferes with hypoxia signaling during colonic inflammation
(FapUNIFESP (SciELO), 2014)Context Intestinal inflammation can induce a local reduction in oxygen levels that triggers an adaptive response centered on the expression of hypoxia-inducible factors (HIFs). Nitric oxide, a well-described inflammatory ... -
Anti-inflammatory effects of yerba maté extract (Ilex paraguariensis) ameliorate insulin resistance in mice with high fat diet-induced obesity
(Elsevier BV, 2011)The aim of the present study was to evaluate the effects of yerba maté extract upon markers of insulin resistance and inflammatory markers in mice with high fat diet-induced obesity. The mice were introduced to either ... -
Expression of Toll-Like receptors in enterocromaffin-like cells and their function in histamine release
(Springer Science and Business Media LLC, 2012)Introduction Enterocromaffin-like cells (ECL) are specialized endocrine gastric cells able to release histamine, which in turn controls gastric acid production by parietal cells. Helicobacter pylori infection and other ... -
Perinodal adipose tissue and mesenteric lymph node activation during reactivated TNBS-colitis in rats
(Springer Science and Business Media LLC, 2011)Background Colitis induced by trinitrobenzene sulfonic acid (TNBS) with reactivation is a good experimental model for studying inflammatory bowel disease pathogenesis and appropriate therapeutics. This experimental model ... -
Phenolic compounds from maté (Ilex paraguariensis) inhibit adipogenesis in 3T3-L1 preadipocytes
(Springer Science and Business Media LLC, 2012)Leaves of Ilex paraguariensis are used to prepare a tea known as maté which is a common beverage in several South American countries. The ethanol extract was fractionated to identify the compounds responsible for the ...